| dc.contributor.author | Schaefers, Matthew M | |
| dc.contributor.author | Wang, Benjamin X | |
| dc.contributor.author | Boisvert, Nicole M | |
| dc.contributor.author | Martini, Sarah J | |
| dc.contributor.author | Bonney, Sarah L | |
| dc.contributor.author | Marshall, Christopher W | |
| dc.contributor.author | Laub, Michael T | |
| dc.contributor.author | Cooper, Vaughn S | |
| dc.contributor.author | Priebe, Gregory P | |
| dc.date.accessioned | 2022-12-13T18:34:47Z | |
| dc.date.available | 2022-12-13T18:34:47Z | |
| dc.date.issued | 2021 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/146863 | |
| dc.description.abstract | <jats:p>
Infections caused by members of the
<jats:named-content content-type="genus-species">Burkholderia cepacia</jats:named-content>
complex (BCC) are a serious concern for patients with cystic fibrosis (CF) as these bacteria are often resistant to many antibiotics. During long-term infection of CF patients with BCC, mutations in genes encoding the FixLJ system often become prevalent, suggesting that these changes may benefit the bacteria during infection.
</jats:p> | en_US |
| dc.language.iso | en | |
| dc.publisher | American Society for Microbiology | en_US |
| dc.relation.isversionof | 10.1128/MBIO.01823-21 | en_US |
| dc.rights | Creative Commons Attribution 4.0 International license | en_US |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_US |
| dc.source | American Society for Microbiology | en_US |
| dc.title | Evolution towards Virulence in a Burkholderia Two-Component System | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Schaefers, Matthew M, Wang, Benjamin X, Boisvert, Nicole M, Martini, Sarah J, Bonney, Sarah L et al. 2021. "Evolution towards Virulence in a Burkholderia Two-Component System." mBio, 12 (4). | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.relation.journal | mBio | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2022-12-13T18:23:39Z | |
| dspace.orderedauthors | Schaefers, MM; Wang, BX; Boisvert, NM; Martini, SJ; Bonney, SL; Marshall, CW; Laub, MT; Cooper, VS; Priebe, GP | en_US |
| dspace.date.submission | 2022-12-13T18:23:41Z | |
| mit.journal.volume | 12 | en_US |
| mit.journal.issue | 4 | en_US |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Authority Work and Publication Information Needed | en_US |
