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A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP

dc.contributor.authorShahsavari, Negar
dc.contributor.authorWang, Boyuan
dc.contributor.authorImai, Yu
dc.contributor.authorMori, Miho
dc.contributor.authorSon, Sangkeun
dc.contributor.authorLiang, Libang
dc.contributor.authorBöhringer, Nils
dc.contributor.authorManuse, Sylvie
dc.contributor.authorGates, Michael F
dc.contributor.authorMorrissette, Madeleine
dc.contributor.authorCorsetti, Rachel
dc.contributor.authorEspinoza, Josh L
dc.contributor.authorDupont, Chris L
dc.contributor.authorLaub, Michael T
dc.contributor.authorLewis, Kim
dc.date.accessioned2022-12-13T18:50:01Z
dc.date.available2022-12-13T18:50:01Z
dc.date.issued2022
dc.identifier.urihttps://hdl.handle.net/1721.1/146865
dc.description.abstract<jats:p> Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on <jats:italic>Photorhabdus</jats:italic> , gut symbionts of enthomopathogenic nematodes that carry up to 40 biosynthetic gene clusters coding for secondary metabolites. </jats:p>en_US
dc.language.isoen
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.isversionof10.1128/MBIO.00700-22en_US
dc.rightsCreative Commons Attribution 4.0 International licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourceAmerican Society for Microbiologyen_US
dc.titleA Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTPen_US
dc.typeArticleen_US
dc.identifier.citationShahsavari, Negar, Wang, Boyuan, Imai, Yu, Mori, Miho, Son, Sangkeun et al. 2022. "A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP." mBio, 13 (3).
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biologyen_US
dc.relation.journalmBioen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2022-12-13T18:38:54Z
dspace.orderedauthorsShahsavari, N; Wang, B; Imai, Y; Mori, M; Son, S; Liang, L; Böhringer, N; Manuse, S; Gates, MF; Morrissette, M; Corsetti, R; Espinoza, JL; Dupont, CL; Laub, MT; Lewis, Ken_US
dspace.date.submission2022-12-13T18:38:56Z
mit.journal.volume13en_US
mit.journal.issue3en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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