The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

Author(s)
Wang, Chuangqi; Li, Yijia; Kaplonek, Paulina; Gentili, Matteo; Fischinger, Stephanie; ... Show more
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Abstract
<jats:p>We showed that persistent SARS-CoV-2 RNAemia is an independent predictor of severe COVID-19. We observed that SARS-CoV-2-targeted antibody maturation, specifically Fc-effector functions rather than neutralization, was strongly linked with the ability to rapidly clear viremia.</jats:p>
Date issued
2022
URI
https://hdl.handle.net/1721.1/147856
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
mBio
Publisher
American Society for Microbiology
Citation
Wang, Chuangqi, Li, Yijia, Kaplonek, Paulina, Gentili, Matteo, Fischinger, Stephanie et al. 2022. "The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia." mBio, 13 (4).
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