Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity

Author(s)
Bowman, Kathryn A; Stein, Daniel; Shin, Sally; Ferbas, Kathie G; Tobin, Nicole H; ... Show more
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Abstract
<jats:p>Recent data indicates improved immunity to SARS-CoV-2 in individuals who experience a combination of two mRNA vaccine doses and infection, “hybrid immunity,” compared to individuals who receive vaccination or experience infection alone. While previous infection accelerates the vaccine-induced immune response following the first dose of mRNA vaccination, subsequent doses demonstrate negligible increases in antibody titers or T cell immunity.</jats:p>
Date issued
2022
URI
https://hdl.handle.net/1721.1/147858
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
mBio
Publisher
American Society for Microbiology
Citation
Bowman, Kathryn A, Stein, Daniel, Shin, Sally, Ferbas, Kathie G, Tobin, Nicole H et al. 2022. "Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity." mBio, 13 (5).
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