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Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity

dc.contributor.authorBowman, Kathryn A
dc.contributor.authorStein, Daniel
dc.contributor.authorShin, Sally
dc.contributor.authorFerbas, Kathie G
dc.contributor.authorTobin, Nicole H
dc.contributor.authorMann, Colin
dc.contributor.authorFischinger, Stephanie
dc.contributor.authorOllmann Saphire, Erica
dc.contributor.authorLauffenburger, Douglas
dc.contributor.authorRimoin, Anne W
dc.contributor.authorAldrovandi, Grace
dc.contributor.authorAlter, Galit
dc.date.accessioned2023-02-03T16:58:26Z
dc.date.available2023-02-03T16:58:26Z
dc.date.issued2022
dc.identifier.urihttps://hdl.handle.net/1721.1/147858
dc.description.abstract<jats:p>Recent data indicates improved immunity to SARS-CoV-2 in individuals who experience a combination of two mRNA vaccine doses and infection, “hybrid immunity,” compared to individuals who receive vaccination or experience infection alone. While previous infection accelerates the vaccine-induced immune response following the first dose of mRNA vaccination, subsequent doses demonstrate negligible increases in antibody titers or T cell immunity.</jats:p>en_US
dc.language.isoen
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.isversionof10.1128/MBIO.01647-22en_US
dc.rightsCreative Commons Attribution 4.0 International licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourcemBioen_US
dc.titleHybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunityen_US
dc.typeArticleen_US
dc.identifier.citationBowman, Kathryn A, Stein, Daniel, Shin, Sally, Ferbas, Kathie G, Tobin, Nicole H et al. 2022. "Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity." mBio, 13 (5).
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.relation.journalmBioen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2023-02-03T16:55:06Z
dspace.orderedauthorsBowman, KA; Stein, D; Shin, S; Ferbas, KG; Tobin, NH; Mann, C; Fischinger, S; Ollmann Saphire, E; Lauffenburger, D; Rimoin, AW; Aldrovandi, G; Alter, Gen_US
dspace.date.submission2023-02-03T16:55:09Z
mit.journal.volume13en_US
mit.journal.issue5en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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