| dc.contributor.author | Rochman, Nash D | |
| dc.contributor.author | Faure, Guilhem | |
| dc.contributor.author | Wolf, Yuri I | |
| dc.contributor.author | Freddolino, Peter L | |
| dc.contributor.author | Zhang, Feng | |
| dc.contributor.author | Koonin, Eugene V | |
| dc.date.accessioned | 2023-04-04T17:19:38Z | |
| dc.date.available | 2023-04-04T17:19:38Z | |
| dc.date.issued | 2022-04-26 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/150406 | |
| dc.description.abstract | <jats:p>Emergence of vaccine escape variants of SARS-CoV-2 is arguably the most pressing problem during the COVID-19 pandemic as vaccines are distributed worldwide. We employed a computational approach to assess the risk of antibody escape resulting from mutations in the receptor-binding domain of the spike protein of the wild-type SARS-CoV-2 virus as well as the Delta, Gamma, and Omicron variants.</jats:p> | en_US |
| dc.language.iso | en | |
| dc.publisher | American Society for Microbiology | en_US |
| dc.relation.isversionof | 10.1128/mbio.00135-22 | en_US |
| dc.rights | Creative Commons Attribution | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
| dc.source | ASM | en_US |
| dc.title | Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Rochman, Nash D, Faure, Guilhem, Wolf, Yuri I, Freddolino, Peter L, Zhang, Feng et al. 2022. "Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape." mBio, 13 (2). | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences | en_US |
| dc.relation.journal | mBio | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2023-04-04T17:17:02Z | |
| dspace.orderedauthors | Rochman, ND; Faure, G; Wolf, YI; Freddolino, PL; Zhang, F; Koonin, EV | en_US |
| dspace.date.submission | 2023-04-04T17:17:05Z | |
| mit.journal.volume | 13 | en_US |
| mit.journal.issue | 2 | en_US |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Authority Work and Publication Information Needed | en_US |
