Comparative genomic workflow
Author(s)Rajapakse, Jagath; Pooja; Chen, Chunxi; Ho, Sy-Loi
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his article describes a workflow for identifying conserved patterns in noncoding regions of vertebrate genomes, with an intention of investigating possible functions of the conserved regions. The annotations of genomes are collected from the Ensembl database. The sequences are then arranged to use for sequence alignment with basic local alignment search tool Z (BLASTZ) , which finds gap- free alignments of at least q% identity and I b/s in length. All the conserved noncoding regions identified are stored in a relational database. An user-friendly Web interface provides easy access to conserved regions and related information and visualization capabilities.
DepartmentMassachusetts Institute of Technology. Department of Biological Engineering
IEEE Engineering in Medicine and Biology Magazine
Institute of Electrical and Electronics Engineers
Rajapakse, J. et al. “Comparative genomic workflow.” Engineering in Medicine and Biology Magazine, IEEE 28.4 (2009): 19-24. ©2009 IEEE.
Final published version
INSPEC Accession Number: 10781332