| dc.contributor.author | Shu, K. | |
| dc.contributor.author | Thatte, H. | |
| dc.contributor.author | Spector, Myron | |
| dc.date.accessioned | 2011-03-10T21:07:26Z | |
| dc.date.available | 2011-03-10T21:07:26Z | |
| dc.date.issued | 2009-05 | |
| dc.date.submitted | 2009-04 | |
| dc.identifier.isbn | 978-1-4244-4362-8 | |
| dc.identifier.other | INSPEC Accession Number: 10666570 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/61655 | |
| dc.description.abstract | Mesenchymal stem cell (MSC) contraction associated with chondrogenesis is attributed to the expression of alpha-smooth muscle actin (alpha-SMA). In this study, pluripotent embryonic carcinoma cells (ECCs) and MSCs were compared for cartilage histogensis. Both cell types expressed alpha-SMA in monolayer. However, when cultured in pellets and in 3-D scaffolds, only MSCs contracted and formed glycosaminoglycan (GAG)- and type II collagen-rich tissue. Under these culture conditions, MSCs appear to be superior over ECCs for cartilage regeneration. | en_US |
| dc.description.sponsorship | United States. Dept. of Veteran Affairs | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Electrical and Electronics Engineers | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1109/NEBC.2009.4967739 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | IEEE | en_US |
| dc.title | Chondrogenic Differentiation of Adult Mesenchymal Stem Cells and Embryonic Stem Cells | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Shu, K., H. Thatte, and M. Spector. “Chondrogenic differentiation of adult mesenchymal stem cells and embryonic stem cells.” Bioengineering Conference, 2009 IEEE 35th Annual Northeast. 2009. 1-2. © 2009 IEEE. | en_US |
| dc.contributor.department | Harvard University--MIT Division of Health Sciences and Technology | en_US |
| dc.contributor.approver | Spector, Myron | |
| dc.contributor.mitauthor | Spector, Myron | |
| dc.contributor.mitauthor | Shu, K. | |
| dc.contributor.mitauthor | Thatte, H. | |
| dc.relation.journal | IEEE 35th Annual Northeast Bioengineering Conference, 2009 | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/ConferencePaper | en_US |
| dspace.orderedauthors | Shu, K.; Thatte, H.; Spector, M. | en |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
