| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.contributor.author | Senecal, Todd D. | |
| dc.contributor.author | Parsons, Andrew | |
| dc.date.accessioned | 2012-08-02T18:42:27Z | |
| dc.date.available | 2012-08-02T18:42:27Z | |
| dc.date.issued | 2011-01 | |
| dc.date.submitted | 2010-11 | |
| dc.identifier.issn | 0022-3263 | |
| dc.identifier.issn | 1520-6904 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/71959 | |
| dc.description.abstract | A method for the room temperature copper-mediated trifluoromethylation of aryl and heteroaryl boronic acids has been developed. This protocol is amenable to normal benchtop setup and reactions typically require only 1−4 h. Proceeding under mild conditions, the method tolerates a range of functional groups, allowing access to a variety of trifluoromethylarenes. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (grant no. GM-46059) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (grant no. 1F32GM093532) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (grant no. CHE-9808061) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (grant no. DBI-9729592) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/jo1023377 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Room Temperature Aryl Trifluoromethylation via Copper- Mediated Oxidative Cross-Coupling | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Buchwald, Stephen Leffler, Andrew T. Parsons, and Todd D. Senecal. "Room Temperature Aryl Trifluoromethylation via Copper-Mediated Oxidative Cross-Coupling." The Journal of Organic Chemistry 76.4 (2011): 1174-1176. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.approver | Buchwald, Stephen L. | |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | |
| dc.contributor.mitauthor | Senecal, Todd D. | |
| dc.contributor.mitauthor | Parsons, Andrew | |
| dc.relation.journal | Journal of Organic Chemistry | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Senecal, Todd D.; Parsons, Andrew T.; Buchwald, Stephen L. | en |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
