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Efficient replication bypass of size-expanded DNA base pairs in bacterial cells

dc.contributor.authorDelaney, James C.
dc.contributor.authorGao, Jianmin
dc.contributor.authorLiu, Haibo
dc.contributor.authorShrivastav, Nidhi
dc.contributor.authorEssigmann, John M.
dc.contributor.authorKool, Eric T.
dc.date.accessioned2012-12-12T18:48:18Z
dc.date.available2012-12-12T18:48:18Z
dc.date.issued2009-05
dc.identifier.issn0044-8249
dc.identifier.issn1521-3757
dc.identifier.urihttp://hdl.handle.net/1721.1/75427
dc.descriptionAuthor Manuscript 2012 September 06en_US
dc.description.abstractSupersize me! Size-expanded DNA bases (xDNA) are able to encode natural DNA sequences in replication. In vitro experiments with a DNA polymerase show nucleotide incorporation opposite the xDNA bases with correct pairing. In vivo experiments using E. coli show that two xDNA bases (xA and xC, see picture) encode the correct replication partners.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (CA80024)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (GM63587)en_US
dc.description.sponsorshipStanford Graduate Fellowshipen_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/anie.200805683en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alike 3.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.sourcePMCen_US
dc.titleEfficient replication bypass of size-expanded DNA base pairs in bacterial cellsen_US
dc.typeArticleen_US
dc.identifier.citationDelaney, James C. et al. “Efficient Replication Bypass of Size-Expanded DNA Base Pairs in Bacterial Cells.” Angewandte Chemie International Edition 48.25 (2009): 4524–4527.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.mitauthorDelaney, James C.
dc.contributor.mitauthorShrivastav, Nidhi
dc.contributor.mitauthorEssigmann, John M.
dc.relation.journalAngewandte Chemieen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsDelaney, James C.; Gao, Jianmin; Liu, Haibo; Shrivastav, Nidhi; Essigmann, John M.; Kool, Eric T.en
dc.identifier.orcidhttps://orcid.org/0000-0001-6159-0778
dc.identifier.orcidhttps://orcid.org/0000-0002-2196-5691
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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