dc.contributor.author | Drake, Adam | |
dc.contributor.author | Browne, Edward P. | |
dc.contributor.author | Phennicie, Ryan T. | |
dc.contributor.author | Chen, Jianzhu | |
dc.date.accessioned | 2013-01-30T18:41:08Z | |
dc.date.available | 2013-01-30T18:41:08Z | |
dc.date.issued | 2012-09 | |
dc.identifier.issn | 1742-4690 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/76670 | |
dc.description.abstract | Lentiviral entry to quiescent lymphocytes represents a 'time bomb' waiting for cellular activation to spread infection. In order to undergo immune activation T cells interact with dendritic cells presenting peptide:MHC complexes 'sampling' them to look for agonist peptides and receiving survival signals from self peptides. This makes the dendritic cell:T cell interaction an ideal checkpoint to contain lentiviral infection of quiescent lypmhocytes. | en_US |
dc.language.iso | en_US | |
dc.publisher | Biomed Central Ltd. | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1186/1742-4690-9-s2-p178 | en_US |
dc.rights | Creative Commons Attribution | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/2.0 | en_US |
dc.source | BioMed Central | en_US |
dc.title | Dendritic cell nediated inhibition of lentiviral infection | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Drake, A et al. “Dendritic Cell Nediated Inhibition of Lentiviral Infection.” Retrovirology 9.Suppl 2 (2012): P178. | en_US |
dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
dc.contributor.mitauthor | Drake, Adam | |
dc.contributor.mitauthor | Browne, Edward P. | |
dc.contributor.mitauthor | Phennicie, Ryan T. | |
dc.contributor.mitauthor | Chen, J. | |
dc.relation.journal | Retrovirology | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Drake, A; Browne, E; Phennicie, R; Chen, J | en |
dc.identifier.orcid | https://orcid.org/0000-0002-5687-6154 | |
mit.license | PUBLISHER_CC | en_US |
mit.metadata.status | Complete | |