| dc.contributor.author | Del Vecchio, Domitilla | |
| dc.date.accessioned | 2013-04-26T15:35:16Z | |
| dc.date.available | 2013-04-26T15:35:16Z | |
| dc.date.issued | 2010-10 | |
| dc.identifier.isbn | 978-1-4244-7746-3 | |
| dc.identifier.isbn | 978-1-4244-7745-6 | |
| dc.identifier.issn | 0743-1546 | |
| dc.identifier.other | INSPEC Accession Number: 11848955 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/78618 | |
| dc.description.abstract | It was theoretically shown that impedance-like effects, called retroactivity, in biomolecular circuits can significantly impact the behavior of a system. In this paper, we quantify the effect of retroactivity on the transfer function of a phosphorylation system after linearization of its nonlinear model about a steady state. Our analysis shows that retroactivity shifts the poles of the transfer function toward the low frequency. | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Electrical and Electronics Engineers | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1109/CDC.2010.5717674 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | IEEE | en_US |
| dc.title | The effect of retroactivity on the transfer function of a phosphorylation system | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Del Vecchio, Domitilla. "The Effect of Retroactivity on the Transfer Function of a Phosphorylation System." In 49th IEEE Conference on Decision and Control, December 15-17, 2010, Hilton Atlanta Hotel, Atlanta, GA, USA, 2010, IEEE, Pp. 2523–2528. Web. © Copyright 2010 IEEE. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Mechanical Engineering | en_US |
| dc.contributor.mitauthor | Del Vecchio, Domitilla | |
| dc.relation.journal | Proceedings of the 49th IEEE Conference on Decision and Control (CDC), 2010 | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/ConferencePaper | en_US |
| dspace.orderedauthors | Del Vecchio, Domitilla | en |
| dc.identifier.orcid | https://orcid.org/0000-0001-6472-8576 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
