Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds
Author(s)
Goodell, John R.; McMullen, Jonathan P.; Zaborenko, Nikolay; Maloney, Jason R.; Ho, Chuan-Xing; Jensen, Klavs F.; Porco, John A.; Beeler, Aaron B.; ... Show more Show less
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Show full item recordAbstract
An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo [3.2.1] octanoid scaffolds will be described.
Date issued
2009-08Department
Massachusetts Institute of Technology. Department of Chemical EngineeringJournal
Journal of Organic Chemistry
Publisher
American Chemical Society
Citation
Goodell, John R., Jonathan P. McMullen, Nikolay Zaborenko, Jason R. Maloney, Chuan-Xing Ho, Klavs F. Jensen, John A. Porco, and Aaron B. Beeler. "Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds." Journal of Organic Chemistry 74, no. 16 (August 21, 2009): 6169-6180.
Version: Author's final manuscript
ISSN
0022-3263
1520-6904