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dc.contributor.authorGoodell, John R.
dc.contributor.authorMcMullen, Jonathan P.
dc.contributor.authorZaborenko, Nikolay
dc.contributor.authorMaloney, Jason R.
dc.contributor.authorHo, Chuan-Xing
dc.contributor.authorJensen, Klavs F.
dc.contributor.authorPorco, John A.
dc.contributor.authorBeeler, Aaron B.
dc.date.accessioned2013-06-20T14:12:57Z
dc.date.available2013-06-20T14:12:57Z
dc.date.issued2009-08
dc.date.submitted2009-05
dc.identifier.issn0022-3263
dc.identifier.issn1520-6904
dc.identifier.urihttp://hdl.handle.net/1721.1/79348
dc.description.abstractAn automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo [3.2.1] octanoid scaffolds will be described.en_US
dc.description.sponsorshipNational Institute of General Medical Sciences (U.S.) (CMLD Initiative (P50 GM067041))en_US
dc.description.sponsorshipPfizer Inc.en_US
dc.description.sponsorshipMerck Research Laboratoriesen_US
dc.description.sponsorshipNational Science Foundation (U.S.) (NSF-REU program (CHE-0649114))en_US
dc.language.isoen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/jo901073ven_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourcePMCen_US
dc.titleDevelopment of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffoldsen_US
dc.typeArticleen_US
dc.identifier.citationGoodell, John R., Jonathan P. McMullen, Nikolay Zaborenko, Jason R. Maloney, Chuan-Xing Ho, Klavs F. Jensen, John A. Porco, and Aaron B. Beeler. "Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds." Journal of Organic Chemistry 74, no. 16 (August 21, 2009): 6169-6180.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.mitauthorMcMullen, Jonathan P.en_US
dc.contributor.mitauthorJensen, Klavs F.en_US
dc.contributor.mitauthorZaborenko, Nikolayen_US
dc.relation.journalJournal of Organic Chemistryen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsGoodell, John R.; McMullen, Jonathan P.; Zaborenko, Nikolay; Maloney, Jason R.; Ho, Chuan-Xing; Jensen, Klavs F.; Porco, John A.; Beeler, Aaron B.en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-7192-580X
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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