| dc.contributor.author | DeMuth, Peter Charles | |
| dc.contributor.author | Su, Xingfang | |
| dc.contributor.author | Samuel, Raymond E. | |
| dc.contributor.author | Hammond, Paula T | |
| dc.contributor.author | Irvine, Darrell J | |
| dc.date.accessioned | 2013-06-26T16:33:34Z | |
| dc.date.available | 2013-06-26T16:33:34Z | |
| dc.date.issued | 2010-11 | |
| dc.date.submitted | 2010-07 | |
| dc.identifier.issn | 09359648 | |
| dc.identifier.issn | 1521-4095 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/79375 | |
| dc.description.abstract | Multilayer-coated microneedles achieve transcutaneous delivery of plasmid DNA to the viable epidermis. Cy3-labeled plasmid DNA encoding luciferase (yellow) is deposited on biodegradable microneedle arrays through multilayer self-assembly and then delivered to the skin by microneedle application to achieve colocalization with Langerhans dendritic cells (MHC II-GFP–green). | en_US |
| dc.description.sponsorship | United States. Dept. of Defense (DAAD19- 02-D-0002) | en_US |
| dc.description.sponsorship | United States. Dept. of Defense (W911NF-07-D-0004) | en_US |
| dc.description.sponsorship | Ragon Institute of MGH, MIT and Harvard | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (NIH Biotechnology Training Program at MIT) | en_US |
| dc.description.sponsorship | Howard Hughes Medical Institute (Investigator) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley-Blackwell Publishers | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/adma.201001525 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | DeMuth, Peter C., Xingfang Su, Raymond E. Samuel, Paula T. Hammond, and Darrell J. Irvine. Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA. Advanced Materials 22, no. 43 (November 16, 2010): 4851-4856. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biological Engineering | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Materials Science and Engineering | en_US |
| dc.contributor.department | Ragon Institute of MGH, MIT and Harvard | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.mitauthor | DeMuth, Peter Charles | en_US |
| dc.contributor.mitauthor | Su, Xingfang | en_US |
| dc.contributor.mitauthor | Samuel, Raymond E. | en_US |
| dc.contributor.mitauthor | Hammond, Paula T. | en_US |
| dc.contributor.mitauthor | Irvine, Darrell J. | en_US |
| dc.relation.journal | Advanced Materials | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | DeMuth, Peter C.; Su, Xingfang; Samuel, Raymond E.; Hammond, Paula T.; Irvine, Darrell J. | en_US |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
