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dc.contributor.authorMcGowan, Meredeth A.
dc.contributor.authorHenderson, Jaclyn L.
dc.contributor.authorBuchwald, Stephen Leffler
dc.date.accessioned2013-11-01T16:29:41Z
dc.date.available2013-11-01T16:29:41Z
dc.date.issued2012-03
dc.date.submitted2012-01
dc.identifier.issn1523-7060
dc.identifier.issn1523-7052
dc.identifier.urihttp://hdl.handle.net/1721.1/81945
dc.description.abstractA method for the Pd-catalyzed coupling of 2-aminothiazole derivatives with aryl bromides and triflates is described. Significantly, for this class of nucleophiles, the coupling exhibits a broad substrate scope and proceeds with a reasonable catalyst loading. Furthermore, an interesting effect of acetic acid as an additive is uncovered that facilitates catalyst activation.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant GM 58160)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Postdoctoral Fellowship F32GM097771)en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (CHE-9808061)en_US
dc.language.isoen_US
dc.publisherAmerican Chemical Society (ACS)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/ol300178jen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourcePMCen_US
dc.titlePalladium-Catalyzed N-Arylation of 2-Aminothiazolesen_US
dc.typeArticleen_US
dc.identifier.citationMcGowan, Meredeth A., Jaclyn L. Henderson, and Stephen L. Buchwald. “Palladium-Catalyzed N-Arylation of 2-Aminothiazoles.” Organic Letters 14, no. 6 (March 16, 2012): 1432-1435.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.mitauthorMcGowan, Meredeth A.en_US
dc.contributor.mitauthorHenderson, Jaclyn L.en_US
dc.contributor.mitauthorBuchwald, Stephen Leffleren_US
dc.relation.journalOrganic Lettersen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsMcGowan, Meredeth A.; Henderson, Jaclyn L.; Buchwald, Stephen L.en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-3875-4775
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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