| dc.contributor.author | Biscoe, Mark R. | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2013-11-13T16:24:20Z | |
| dc.date.available | 2013-11-13T16:24:20Z | |
| dc.date.issued | 2009-03 | |
| dc.date.submitted | 2009-02 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/82105 | |
| dc.description.abstract | Simple, efficient procedures for the monoarylation of acetate esters and aryl methyl ketones using aryl chlorides are presented. Previously, no general method was available to ensure the highly selective monoarylation of these classes of substrates using aryl chlorides. Using palladium precatalysts recently reported by our group, these reactions are easily accomplished under mild conditions that tolerate a wide array of heterocyclic substrates. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM-46059) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Postdoctoral Fellowship GM-F32-75685) | en_US |
| dc.description.sponsorship | Merck & Co., Inc. | en_US |
| dc.description.sponsorship | Boehringer Ingelheim Pharmaceuticals | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol900295u | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Selective Monoarylation of Acetate Esters and Aryl Methyl Ketones Using Aryl Chlorides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Biscoe, Mark R., and Stephen L. Buchwald. “Selective Monoarylation of Acetate Esters and Aryl Methyl Ketones Using Aryl Chlorides.” Organic Letters 11, no. 8 (April 16, 2009): 1773-1775. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.contributor.mitauthor | Biscoe, Mark R. | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Biscoe, Mark R.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
