Directed Heterodimerization: Stereocontrolled Assembly via Solvent-Caged Unsymmetrical Diazene Fragmentation

Author(s)
Movassaghi, Mohammad; Ahmad, Omar K.; Lathrop, Stephen
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Abstract
A general strategy for the directed and stereocontrolled assembly of carbon–carbon linked heterodimeric hexahydropyrroloindoles is described. The stepwise union of complex amines in the form of mixed diazenes followed by photoexpulsion of dinitrogen in a solvent cage provides completely guided assembly at challenging C[3 over sp]–C[3 over sp] and C[3 over sp]–C[2 over sp] connections.
Date issued
2011-07
URI
http://hdl.handle.net/1721.1/82464
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Movassaghi, Mohammad, Omar K. Ahmad, and Stephen P. Lathrop. “Directed Heterodimerization: Stereocontrolled Assembly via Solvent-Caged Unsymmetrical Diazene Fragmentation.” Journal of the American Chemical Society 133, no. 33 (August 24, 2011): 13002-13005.
Version: Author's final manuscript
ISSN
0002-7863
1520-5126
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