| dc.contributor.author | Imperiali, Barbara | |
| dc.contributor.author | Socher, Elke Ricarda | |
| dc.date.accessioned | 2014-01-27T18:03:39Z | |
| dc.date.available | 2014-01-27T18:03:39Z | |
| dc.date.issued | 2012-12 | |
| dc.date.submitted | 2012-11 | |
| dc.identifier.issn | 14394227 | |
| dc.identifier.issn | 1439-7633 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/84588 | |
| dc.description.abstract | The FRET-Capture approach exploits a bound solvatochromic fluorophore, 4-N,N-dimethylamino-1,8-naphthalimide, as a FRET donor in both inter- and intramolecular energy transfer. A unique feature of this method is the additional level of signal selectivity as the FRET signal is only turned on when the donor is specifically bound to the protein of interest, eliminating high background and false positive signals. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant R01 EB010246) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/cbic.201200700 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | FRET-Capture: A Sensitive Method for the Detection of Dynamic Protein Interactions | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Socher, Elke, and Barbara Imperiali. “FRET-Capture: A Sensitive Method for the Detection of Dynamic Protein Interactions.” ChemBioChem 14, no. 1 (January 2, 2013): 53-57. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Socher, Elke Ricarda | en_US |
| dc.contributor.mitauthor | Imperiali, Barbara | en_US |
| dc.relation.journal | ChemBioChem | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Socher, Elke; Imperiali, Barbara | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0002-5749-7869 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
