dc.contributor.author | Flygare, Johan | |
dc.contributor.author | Chou, Song | |
dc.contributor.author | Lodish, Harvey F | |
dc.date.accessioned | 2014-02-07T20:40:04Z | |
dc.date.available | 2014-02-07T20:40:04Z | |
dc.date.issued | 2010-03 | |
dc.date.submitted | 2010-02 | |
dc.identifier.issn | 15216543 | |
dc.identifier.issn | 15216551 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/84708 | |
dc.description.abstract | This article reviews the regulation of production of red blood cells at several levels: (1) the ability of erythropoietin and adhesion to a fibronectin matrix to stimulate the rapid production of red cells by inducing terminal proliferation and differentiation of committed erythroid CFU-E progenitors; (2) the regulated expansion of the pool of earlier BFU-E erythroid progenitors by glucocorticoids and other factors that occurs during chronic anemia or inflammation; and (3) the expansion of thehematopoietic cell pool to produce more progenitors of all hematopoietic lineages. | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.) (grant P01 HL 32262) | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.) (grant DK06735) | en_US |
dc.description.sponsorship | Amgen Inc. | en_US |
dc.description.sponsorship | Swedish Research Council | en_US |
dc.description.sponsorship | Maja och Hjalmar Leanders Stiftelse | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.). Ruth L. Kirschstein National Research Service Award | en_US |
dc.description.sponsorship | Sweden-America Foundation | en_US |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1002/iub.322 | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | From stem cell to erythroblast: Regulation of red cell production at multiple levels by multiple hormones | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Lodish, Harvey, Johan Flygare, and Song Chou. “From stem cell to erythroblast: Regulation of red cell production at multiple levels by multiple hormones.” IUBMB Life 62, no. 7 (July 19, 2010): 492-496. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
dc.contributor.mitauthor | Lodish, Harvey F. | en_US |
dc.contributor.mitauthor | Flygare, Johan | en_US |
dc.contributor.mitauthor | Chou, Song | en_US |
dc.relation.journal | IUBMB Life | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Lodish, Harvey; Flygare, Johan; Chou, Song | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-7029-7415 | |
mit.license | OPEN_ACCESS_POLICY | en_US |
mit.metadata.status | Complete | |