| dc.contributor.author | Brasche, Gordon | |
| dc.contributor.author | Garcia-Fortanet, Jorge | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2014-05-21T20:14:04Z | |
| dc.date.available | 2014-05-21T20:14:04Z | |
| dc.date.issued | 2008-06 | |
| dc.date.submitted | 2008-03 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/87074 | |
| dc.description.abstract | The ortho arylation of anilides to form biphenyls via a twofold C−H functionalization/C−C bond-forming process is described. The oxidative coupling takes place in the presence of 5−10 mol % of Pd(OAc)[subscript 2], 10−20 mol % of DMSO, and 4−11 equiv of the aryl substrate in TFA under an oxygen atmosphere. No metal-containing cocatalyst is required. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM46059) | en_US |
| dc.description.sponsorship | German Academic Exchange Service (postdoctoral fellowships) | en_US |
| dc.description.sponsorship | Spain. Ministerio de Educación y Ciencia (postdoctoral fellowships) | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | Merck Research Laboratories | en_US |
| dc.description.sponsorship | Boehringer Ingelheim Pharmaceuticals | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (NSF (CHE 9808061)) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (NSF (DBI 9729592)) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol800619c | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | ACS | en_US |
| dc.title | Twofold C−H Functionalization: Palladium-Catalyzed Ortho Arylation of Anilides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Brasche, Gordon, Jorge Garcia-Fortanet, and Stephen L. Buchwald. “ Twofold C−H Functionalization: Palladium-Catalyzed Ortho Arylation of Anilides.” Org. Lett. 10, no. 11 (June 2008): 2207–2210. © 2008 American Chemical Society. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Brasche, Gordon | en_US |
| dc.contributor.mitauthor | Garcia-Fortanet, Jorge | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Brasche, Gordon; García-Fortanet,, Jorge; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| dspace.mitauthor.error | true | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
