dc.contributor.author | Shapiro, B. J. | |
dc.contributor.author | Friedman, J. | |
dc.contributor.author | Cordero Sanchez, Otto Xavier | |
dc.contributor.author | Preheim, Sarah Pacocha | |
dc.contributor.author | Timberlake, Sonia Crago | |
dc.contributor.author | Szabo, Gitta | |
dc.contributor.author | Polz, Martin F. | |
dc.contributor.author | Alm, Eric J. | |
dc.date.accessioned | 2014-08-13T13:36:32Z | |
dc.date.available | 2014-08-13T13:36:32Z | |
dc.date.issued | 2012-04 | |
dc.date.submitted | 2011-12 | |
dc.identifier.issn | 0036-8075 | |
dc.identifier.issn | 1095-9203 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/88692 | |
dc.description.abstract | Genetic exchange is common among bacteria, but its effect on population diversity during ecological differentiation remains controversial. A fundamental question is whether advantageous mutations lead to selection of clonal genomes or, as in sexual eukaryotes, sweep through populations on their own. Here, we show that in two recently diverged populations of ocean bacteria, ecological differentiation has occurred akin to a sexual mechanism: A few genome regions have swept through subpopulations in a habitat-specific manner, accompanied by gradual separation of gene pools as evidenced by increased habitat specificity of the most recent recombinations. These findings reconcile previous, seemingly contradictory empirical observations of the genetic structure of bacterial populations and point to a more unified process of differentiation in bacteria and sexual eukaryotes than previously thought. | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant DEB-0918333) | en_US |
dc.description.sponsorship | Woods Hole Center for Oceans & Human Health | en_US |
dc.description.sponsorship | Gordon and Betty Moore Foundation | en_US |
dc.description.sponsorship | United States. Dept. of Energy. Genomes To Life | en_US |
dc.language.iso | en_US | |
dc.publisher | American Association for the Advancement of Science (AAAS) | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1126/science.1218198 | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | Population Genomics of Early Events in the Ecological Differentiation of Bacteria | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Shapiro, B. J., et al. "Population Genomics of Early Events in the Ecological Differentiation of Bacteria." Science 6 April 2012: Vol. 336 no. 6077 pp. 48-51. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Biological Engineering | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering | en_US |
dc.contributor.mitauthor | Cordero Sanchez, Otto Xavier | en_US |
dc.contributor.mitauthor | Preheim, Sarah Pacocha | en_US |
dc.contributor.mitauthor | Timberlake, Sonia Crago | en_US |
dc.contributor.mitauthor | Szabo, Gitta | en_US |
dc.contributor.mitauthor | Polz, Martin F. | en_US |
dc.contributor.mitauthor | Alm, Eric J. | en_US |
dc.relation.journal | Science | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Shapiro, B. J.; Friedman, J.; Cordero, O. X.; Preheim, S. P.; Timberlake, S. C.; Szabo, G.; Polz, M. F.; Alm, E. J. | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-8294-9364 | |
dc.identifier.orcid | https://orcid.org/0000-0001-9296-3733 | |
mit.license | OPEN_ACCESS_POLICY | en_US |
mit.metadata.status | Complete | |