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Core-Shell Hydrogel Microcapsules for Improved Islets Encapsulation

dc.contributor.authorMa, Minglin
dc.contributor.authorChiu, Alan
dc.contributor.authorSahay, Gaurav
dc.contributor.authorDoloff, Joshua C.
dc.contributor.authorDholakia, Nimit
dc.contributor.authorThakrar, Raj
dc.contributor.authorVegas, Arturo
dc.contributor.authorChen, Delai
dc.contributor.authorBratlie, Kaitlin M.
dc.contributor.authorDang, Tram T.
dc.contributor.authorYork, Roger Louis
dc.contributor.authorHollister-Lock, Jennifer
dc.contributor.authorWeir, Gordon C.
dc.contributor.authorAnderson, Daniel Griffith
dc.contributor.authorCohen, Joshua, 1951-
dc.date.accessioned2014-10-30T13:55:48Z
dc.date.available2014-10-30T13:55:48Z
dc.date.issued2013-05
dc.date.submitted2012-09
dc.identifier.issn21922640
dc.identifier.urihttp://hdl.handle.net/1721.1/91236
dc.description.abstractIslets microencapsulation holds great promise to treat type 1 diabetes. Currently used alginate microcapsules often have islets protruding outside capsules, leading to inadequate immuno-protection. A novel design of microcapsules with core–shell structures using a two-fluid co-axial electro-jetting is reported. Improved encapsulation and diabetes correction is achieved in a single step by simply confining the islets in the core region of the capsules.en_US
dc.description.sponsorshipJuvenile Diabetes Research Foundation International (grant 17-2007-1063)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Postdoctoral Fellowship F32 EB011580- 01)en_US
dc.description.sponsorshipTayebati Family Foundationen_US
dc.language.isoen_US
dc.publisherWiley-VCH Verlag GmbH & Co.en_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/adhm.201200341en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleCore-Shell Hydrogel Microcapsules for Improved Islets Encapsulationen_US
dc.typeArticleen_US
dc.identifier.citationMa, Minglin, Alan Chiu, Gaurav Sahay, Joshua C. Doloff, Nimit Dholakia, Raj Thakrar, Joshua Cohen, et al. “Core-Shell Hydrogel Microcapsules for Improved Islets Encapsulation.” Advanced Healthcare Materials 2, no. 5 (December 3, 2012): 667–672.en_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.departmentKoch Institute for Integrative Cancer Research at MITen_US
dc.contributor.mitauthorMa, Minglinen_US
dc.contributor.mitauthorChiu, Alanen_US
dc.contributor.mitauthorSahay, Gauraven_US
dc.contributor.mitauthorDoloff, Joshua C.en_US
dc.contributor.mitauthorDholakia, Nimiten_US
dc.contributor.mitauthorThakrar, Rajen_US
dc.contributor.mitauthorVegas, Arturoen_US
dc.contributor.mitauthorChen, Delaien_US
dc.contributor.mitauthorDang, Tram T.en_US
dc.contributor.mitauthorYork, Roger Louisen_US
dc.contributor.mitauthorAnderson, Daniel Griffithen_US
dc.relation.journalAdvanced Healthcare Materialsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsMa, Minglin; Chiu, Alan; Sahay, Gaurav; Doloff, Joshua C.; Dholakia, Nimit; Thakrar, Raj; Cohen, Joshua; Vegas, Arturo; Chen, Delai; Bratlie, Kaitlin M.; Dang, Tram; York, Roger L.; Hollister-Lock, Jennifer; Weir, Gordon C.; Anderson, Daniel G.en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-2100-1171
dc.identifier.orcidhttps://orcid.org/0000-0001-5629-4798
dc.identifier.orcidhttps://orcid.org/0000-0002-4323-3264
dc.identifier.orcidhttps://orcid.org/0000-0001-9522-8208
dspace.mitauthor.errortrue
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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