A Radical Role for TOR in Longevity

Author(s)
Lamming, Dudley W.; Sabatini, David M.; Sabatini, David
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Abstract
TOR (target of rapamycin) signaling regulates life span in many organisms, but the mechanism behind the effect is unknown. In this issue of Cell Metabolism, Pan and colleagues (2011) find that reduced TORC1 activity promotes yeast life span via a mechanism that, paradoxically, relies upon the production of normally deleterious reactive oxygen species.
Date issued
2011-06
URI
http://hdl.handle.net/1721.1/92330
Department
Massachusetts Institute of Technology. Department of Biology; Whitehead Institute for Biomedical Research; Koch Institute for Integrative Cancer Research at MIT
Journal
Cell Metabolism
Publisher
Elsevier
Citation
Lamming, Dudley W., and David M. Sabatini. “A Radical Role for TOR in Longevity.” Cell Metabolism 13, no. 6 (June 2011): 617–618. © 2011 Elsevier Inc.
Version: Final published version
ISSN
15504131
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