| dc.contributor.author | Zhu, Shaolin | |
| dc.contributor.author | Niljianskul, Nootaree | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2015-02-12T18:23:00Z | |
| dc.date.available | 2015-02-12T18:23:00Z | |
| dc.date.issued | 2013-10 | |
| dc.date.submitted | 2013-09 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/94499 | |
| dc.description.abstract | A highly enantio- and regioselective copper-catalyzed hydroamination reaction of alkenes has been developed using diethoxymethylsilane and esters of hydroxylamines. The process tolerates a wide variety of substituted styrenes, including trans-, cis-, and β,β-disubstituted styrenes, to yield α-branched amines. In addition, aliphatic alkenes coupled to generate exclusively the anti-Markovnikov hydroamination products. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Award GM58160) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja4092819 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Zhu, Shaolin, Nootaree Niljianskul, and Stephen L. Buchwald. “Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes.” Journal of the American Chemical Society 135, no. 42 (October 23, 2013): 15746–15749. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.contributor.mitauthor | Niljianskul, Nootaree | en_US |
| dc.contributor.mitauthor | Zhu, Shaolin | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Zhu, Shaolin; Niljianskul, Nootaree; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
