dc.contributor.author | Israelsen, William James | |
dc.contributor.author | Vander Heiden, Matthew G. | |
dc.date.accessioned | 2015-03-17T17:22:39Z | |
dc.date.available | 2015-03-17T17:22:39Z | |
dc.date.issued | 2010-11 | |
dc.identifier.issn | 00928674 | |
dc.identifier.issn | 1097-4172 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/96047 | |
dc.description.abstract | Cancer cells metabolize glucose by aerobic glycolysis, a phenomenon known as the Warburg effect. Fang et al. (2010) show that the endoplasmic reticulum enzyme ENTPD5 promotes ATP consumption and favors aerobic glycolysis. The findings suggest that nutrient uptake in cancer cells is limited by ATP and satisfies energy requirements other than ATP production. | en_US |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1016/j.cell.2010.11.010 | en_US |
dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
dc.source | Elsevier | en_US |
dc.title | ATP Consumption Promotes Cancer Metabolism | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Israelsen, William J., and Matthew G. Vander Heiden. “ATP Consumption Promotes Cancer Metabolism.” Cell 143, no. 5 (November 2010): 669–671. © 2010 Elsevier Inc. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
dc.contributor.mitauthor | Vander Heiden, Matthew G. | en_US |
dc.contributor.mitauthor | Israelsen, William James | en_US |
dc.relation.journal | Cell | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Israelsen, William J.; Vander Heiden, Matthew G. | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-6702-4192 | |
mit.license | PUBLISHER_POLICY | en_US |
mit.metadata.status | Complete | |