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dc.contributor.authorVictor, Eric
dc.contributor.authorMinier, Mikael Antoine
dc.contributor.authorLippard, Stephen J.
dc.date.accessioned2015-03-30T17:07:15Z
dc.date.available2015-03-30T17:07:15Z
dc.date.issued2014-06
dc.date.submitted2014-10
dc.identifier.issn1434-1948
dc.identifier.issn1099-0682
dc.identifier.urihttp://hdl.handle.net/1721.1/96248
dc.description.abstractNitric oxide is released during the immune response by the host during bacterial infection. To counteract this response, bacteria have evolved nitric oxide reductases to convert NO to N[subscript 2]O. Some of these nitric oxide reductases contain a flavodiiron active site that has bridging carboxylates and hydroxides. Only a handful of synthetic complexes currently exist as models for the protein reactivity. Here, we report the reaction of [Fe[subscript 2](μ-OH)(μ-Ph[subscript 4]DBA)(TMEDA)[subscript 2](OTf)] (4) with NO(g) and Ph[subscript 3]CSNO to prepare the dinitrosyl-triiron complex [Fe[subscript 3](μ-OH)[subscript 2](μ-Ph[subscript 4]DBA)[subscript 2](TMEDA)[subscript 2](NO)[subscript 2]](OTf) (5). The reaction was monitored by UV/Vis and ReactIR spectroscopy, and compound 5 was characterized by X-ray crystallography, [superscript 57]Fe Mossbauer spectroscopy, Evan's method, and FTIR spectroscopy. The IR spectrum of compound 5 compares favorably to experimental spectroscopic data obtained for the proposed mononitrosylated intermediate of the protein.en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant CHE0907905)en_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/ejic.201402543en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceWiley Blackwellen_US
dc.titleSynthesis and Characterization of a Linear Dinitrosyl-Triiron Complex; Comparison to a Flavodiiron Nitric Oxide Reductase Intermediateen_US
dc.title.alternativeSynthesis and Characterization of a Linear Dinitrosyl-Triiron Complexen_US
dc.typeArticleen_US
dc.identifier.citationVictor, Eric, Mikael A. Minier, and Stephen J. Lippard. “Synthesis and Characterization of a Linear Dinitrosyl-Triiron Complex.” European Journal of Inorganic Chemistry 2014.33 (2014): 5640–5645.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.mitauthorLippard, Stephen J.en_US
dc.contributor.mitauthorVictor, Ericen_US
dc.contributor.mitauthorMinier, Mikael Antoineen_US
dc.relation.journalEuropean Journal of Inorganic Chemistryen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsVictor, Eric; Minier, Mikael A.; Lippard, Stephen J.en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-2693-4982
dc.identifier.orcidhttps://orcid.org/0000-0002-8346-9570
mit.licenseOPEN_ACCESS_POLICYen_US


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