| dc.contributor.author | Lee, Hong Geun | |
| dc.contributor.author | Milner, Phillip John | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2015-04-23T18:43:09Z | |
| dc.date.available | 2015-04-23T18:43:09Z | |
| dc.date.issued | 2014-03 | |
| dc.date.submitted | 2014-01 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/96758 | |
| dc.description.abstract | On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits a broad substrate scope, especially with respect to nitrogen-containing heteroaryl bromides, and proceeds with minimal formation of the corresponding reduction products. A facilitated ligand modification process was shown to be critical to the success of the reaction. | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (CHE 0946721) | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Predoctoral fellowship (2010094243)) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Award GM46059) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja5009739 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | American Chemical Society | en_US |
| dc.title | Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Lee, Hong Geun, Phillip J. Milner, and Stephen L. Buchwald. “Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides.” Journal of the American Chemical Society 136, no. 10 (March 12, 2014): 3792–3795. © 2014 American Chemical Society. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Lee, Hong Geun | en_US |
| dc.contributor.mitauthor | Milner, Phillip John | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| dc.identifier.orcid | https://orcid.org/0000-0001-8075-1100 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
