Show simple item record

Extracellular Matrix Heterogeneity Regulates Three-Dimensional Morphologies of Breast Adenocarcinoma Cell Invasion

dc.contributor.authorShin, Yoojin
dc.contributor.authorKim, Hyunju
dc.contributor.authorHan, Sewoon
dc.contributor.authorWon, Jihee
dc.contributor.authorJeong, Hyo Eun
dc.contributor.authorLee, Eun-Sook
dc.contributor.authorKim, Jae-Hong
dc.contributor.authorChung, Seok
dc.contributor.authorKamm, Roger Dale
dc.date.accessioned2015-06-19T18:52:54Z
dc.date.available2015-06-19T18:52:54Z
dc.date.issued2012-11
dc.date.submitted2012-09
dc.identifier.issn21922640
dc.identifier.urihttp://hdl.handle.net/1721.1/97480
dc.description.abstractPlasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully demonstrates the metastatic potential of cancer cells and their effective strategies of ECM proteolytic remodeling and morphological change, while interacting with other cells and invading into heterogeneous ECMs.en_US
dc.description.sponsorshipInternational Research & Development Program (Grant 2009-00631)en_US
dc.description.sponsorshipNational Research Foundation of Korea (Basic Science Research Program Grant 2012-022481)en_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/adhm.201200320en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleExtracellular Matrix Heterogeneity Regulates Three-Dimensional Morphologies of Breast Adenocarcinoma Cell Invasionen_US
dc.typeArticleen_US
dc.identifier.citationShin, Yoojin, Hyunju Kim, Sewoon Han, Jihee Won, Hyo Eun Jeong, Eun-Sook Lee, Roger D. Kamm, Jae-Hong Kim, and Seok Chung. “Extracellular Matrix Heterogeneity Regulates Three-Dimensional Morphologies of Breast Adenocarcinoma Cell Invasion.” Advanced Healthcare Materials 2, no. 6 (November 26, 2012): 790–794.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Mechanical Engineeringen_US
dc.contributor.mitauthorKamm, Roger Daleen_US
dc.relation.journalAdvanced Healthcare Materialsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsShin, Yoojin; Kim, Hyunju; Han, Sewoon; Won, Jihee; Jeong, Hyo Eun; Lee, Eun-Sook; Kamm, Roger D.; Kim, Jae-Hong; Chung, Seoken_US
dc.identifier.orcidhttps://orcid.org/0000-0002-7232-304X
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


Files in this item

Thumbnail
Name:
Kamm_Extracellular matrix.pdf
Size:
357.4Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record