| dc.contributor.author | Yang, Yang | |
| dc.contributor.author | Niedermann, Katrin | |
| dc.contributor.author | Han, Chong | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2015-11-02T19:13:16Z | |
| dc.date.available | 2015-11-02T19:13:16Z | |
| dc.date.issued | 2014-08 | |
| dc.date.submitted | 2014-07 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/99659 | |
| dc.description.abstract | The highly selective palladium-catalyzed Negishi coupling of secondary alkylzinc reagents with heteroaryl halides is described. The development of a series of biarylphosphine ligands has led to the identification of an improved catalyst for the coupling of electron-deficient heterocyclic substrates. Preparation and characterization of oxidative addition complex (L)(Ar)PdBr provided insight into the unique reactivity of catalysts based on CPhos-type ligands in facilitating challenging reductive elimination processes. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant GM46059) | en_US |
| dc.description.sponsorship | Swiss National Science Foundation (Postdoctoral Fellowship) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol502230p | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | ACS | en_US |
| dc.title | Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Yang, Yang, Katrin Niedermann, Chong Han, and Stephen L. Buchwald. “Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides.” Organic Letters 16, no. 17 (September 5, 2014): 4638–4641. © 2014 American Chemical Society | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Yang, Yang | en_US |
| dc.contributor.mitauthor | Niedermann, Katrin | en_US |
| dc.contributor.mitauthor | Han, Chong | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Yang, Yang; Niedermann, Katrin; Han, Chong; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
