| dc.contributor.author | Ernst, Johannes B. | |
| dc.contributor.author | Tay, Nicholas E. S. | |
| dc.contributor.author | Jui, Nathan T. | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2015-11-03T12:44:13Z | |
| dc.date.available | 2015-11-03T12:44:13Z | |
| dc.date.issued | 2014-06 | |
| dc.date.submitted | 2014-05 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/99671 | |
| dc.description.abstract | A direct method for the regioselective construction of benzimidazolones is reported wherein a single palladium catalyst is employed to couple monosubstituted urea substrates with differentially substituted 1,2-dihaloaromatic systems. In this method, the catalyst is able to promote a cascade of two discrete chemoselective C–N bond-forming processes that allows the highly selective and predictable formation of complex heterocycles from simple, readily available starting materials. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Award GM58160) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Award GM099817) | en_US |
| dc.description.sponsorship | Lanxess Corporation | en_US |
| dc.description.sponsorship | Massachusetts Institute of Technology. Undergraduate Research Opportunities Program | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol501531q | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | ACS | en_US |
| dc.title | Regioselective Synthesis of Benzimidazolones via Cascade C–N Coupling of Monosubstituted Ureas | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Ernst, Johannes B., Nicholas E. S. Tay, Nathan T. Jui, and Stephen L. Buchwald. “Regioselective Synthesis of Benzimidazolones via Cascade C–N Coupling of Monosubstituted Ureas.” Organic Letters 16, no. 14 (July 18, 2014): 3844–3846. © 2014 American Chemical Society | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Ernst, Johannes B. | en_US |
| dc.contributor.mitauthor | Tay, Nicholas E. S. | en_US |
| dc.contributor.mitauthor | Jui, Nathan T. | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Ernst, Johannes B.; Tay, Nicholas E. S.; Jui, Nathan T.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
