This is an archived course. A more recent version may be available at ocw.mit.edu.

 

Lecture 8

Lectures: 1 | 2 | 3 | 4-5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 16 | 17 | 19 | 20 | 21 | 22 | 23 | 26

Biomolecular Forces and Energies

  1. Quick Look at Structures of Biomolecules:
    • Small Molecules: Water and Sugars
    • Nucleic Acids: DNA, RNA
    • Polypeptides and Proteins
  2. Review of Molecular Forces
  3. Chemical Forces:
    • Covalent
      • 1 Bond: Vibrational
      • 2 Bonds: Rotational
      • 3 Bonds: Torsional
    • Non-covalent
      • Electrostatic
      • Van der Waals
      • Hydrogen Bond
  4. EntropyAndentropic>=Forces<=:
    • Entropy of Mixing
    • Hydrophobic Effect

Recommended Reading

Protein Physics, Alexei V. Finkelstein and Oleg B. Ptitsyn (Chapters 1-6)

Protein Viewers