This is an archived course. A more recent version may be available at ocw.mit.edu.

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Lecture Notes

Course notes are not available for all class sessions.

Instructors

MK: Prof. Mehran Kardar
LM: Prof. Leonid Mirny

SES # TOPICS INSTRUCTORS
1 Introduction to Course (Material and Organization) MK
2 Molecular Evolution LM
3 Mutations MK
4 Gene Annotation and Similarity Detection LM
5 Substitution Matrices LM
6 Dynamic Programming and Transfer Matrices MK
7 Sequence Alignment and Statistical Physics MK
8 Biomolecular Forces and Energies LM
9 Electrostatics MK
10 Polymer Theory MK
11 Proteins LM
12 The Random Energy Model MK
13 Protein Folding LM
14 Nucleic Acids LM
15 Fluctuating DNA MK
16 RNA LM
17 Protein-DNA Complexes Guest Lecturer: Michael Slutsky
18 Hemoglobin LM
19 Microtubules and Filaments MK
20 Molecular Motors MK
21 Membranes MK
22 Cell Motility MK
23 Networks MK
24 Introduction to Networks LM
25 Dynamics LM
26 Biological Patterns MK