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In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration
| dc.contributor.author | Sangaré, Lamba Omar | |
| dc.contributor.author | Ólafsson, Einar B | |
| dc.contributor.author | Wang, Yifan | |
| dc.contributor.author | Yang, Ninghan | |
| dc.contributor.author | Julien, Lindsay | |
| dc.contributor.author | Camejo, Ana | |
| dc.contributor.author | Pesavento, Patricia | |
| dc.contributor.author | Sidik, Saima M | |
| dc.contributor.author | Lourido, Sebastian | |
| dc.contributor.author | Barragan, Antonio | |
| dc.contributor.author | Saeij, Jeroen PJ | |
| dc.date.accessioned | 2021-09-20T18:23:13Z | |
| dc.date.available | 2021-09-20T18:23:13Z | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/132590 | |
| dc.description.abstract | © 2019 Elsevier Inc. Sangaré et al. use a CRISPR screen to determine the in vivo fitness of Toxoplasma genes. They identify a secreted protein, TgWIP, which determines dendritic cell motility and transmigration in the infected host. In mice, TgWIP determines T. gondii dissemination from the site of infection to distant organs. | en_US |
| dc.language.iso | en | |
| dc.publisher | Elsevier BV | en_US |
| dc.relation.isversionof | 10.1016/J.CHOM.2019.09.008 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration | en_US |
| dc.type | Article | en_US |
| dc.relation.journal | Cell Host and Microbe | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2020-11-12T19:26:20Z | |
| dspace.orderedauthors | Sangaré, LO; Ólafsson, EB; Wang, Y; Yang, N; Julien, L; Camejo, A; Pesavento, P; Sidik, SM; Lourido, S; Barragan, A; Saeij, JPJ | en_US |
| dspace.date.submission | 2020-11-12T19:26:27Z | |
| mit.journal.volume | 26 | en_US |
| mit.journal.issue | 4 | en_US |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Authority Work and Publication Information Needed |
