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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

dc.contributor.authorSeixas, João D
dc.contributor.authorSousa, Bárbara B
dc.contributor.authorMarques, Marta C
dc.contributor.authorGuerreiro, Ana
dc.contributor.authorTraquete, Rui
dc.contributor.authorRodrigues, Tiago
dc.contributor.authorAlbuquerque, Inês S
dc.contributor.authorSousa, Marcos FQ
dc.contributor.authorLemos, Ana R
dc.contributor.authorSousa, Pedro MF
dc.contributor.authorBandeiras, Tiago M
dc.contributor.authorWu, Di
dc.contributor.authorDoyle, Shelby K
dc.contributor.authorRobinson, Carol V
dc.contributor.authorKoehler, Angela N
dc.contributor.authorCorzana, Francisco
dc.contributor.authorMatias, Pedro M
dc.contributor.authorBernardes, Gonçalo JL
dc.date.accessioned2021-10-25T17:40:04Z
dc.date.available2021-10-25T17:40:04Z
dc.date.issued2020
dc.identifier.urihttps://hdl.handle.net/1721.1/133096
dc.description.abstract<p>We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.</p>en_US
dc.language.isoen
dc.publisherRoyal Society of Chemistry (RSC)en_US
dc.relation.isversionof10.1039/D0CB00033Gen_US
dc.rightsCreative Commons Attribution 4.0 International licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourceRoyal Society of Chemistry (RSC)en_US
dc.titleStructural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitorsen_US
dc.typeArticleen_US
dc.identifier.citationSeixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui et al. 2020. "Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors." RSC Chemical Biology, 1 (4).
dc.relation.journalRSC Chemical Biologyen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2021-09-03T18:33:45Z
dspace.orderedauthorsSeixas, JD; Sousa, BB; Marques, MC; Guerreiro, A; Traquete, R; Rodrigues, T; Albuquerque, IS; Sousa, MFQ; Lemos, AR; Sousa, PMF; Bandeiras, TM; Wu, D; Doyle, SK; Robinson, CV; Koehler, AN; Corzana, F; Matias, PM; Bernardes, GJLen_US
dspace.date.submission2021-09-03T18:33:48Z
mit.journal.volume1en_US
mit.journal.issue4en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Neededen_US
mit.metadata.statusAuthority Work and Publication Information Needed


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21721.1/133096.22022-01-24T15:11:21ZPublication information verified/added.
11721.1/133096*2021-10-25T17:40:04Z

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