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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors
Author(s)
Seixas, João D; Sousa, Bárbara B; Marques, Marta C; Guerreiro, Ana; Traquete, Rui; Rodrigues, Tiago; Albuquerque, Inês S; Sousa, Marcos FQ; Lemos, Ana R; Sousa, Pedro MF; Bandeiras, Tiago M; Wu, Di; Doyle, Shelby K; Robinson, Carol V; Koehler, Angela N; Corzana, Francisco; Matias, Pedro M; Bernardes, Gonçalo JL; ... Show more Show less
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Show full item recordAbstract
<p>We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.</p>
Date issued
2020Journal
RSC Chemical Biology
Publisher
Royal Society of Chemistry (RSC)
Citation
Seixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui et al. 2020. "Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors." RSC Chemical Biology, 1 (4).
Version: Final published version