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Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator
dc.date.accessioned | 2021-10-27T19:51:46Z | |
dc.date.available | 2021-10-27T19:51:46Z | |
dc.date.issued | 2020 | |
dc.identifier.uri | https://hdl.handle.net/1721.1/133248 | |
dc.description.abstract | © 2020 Elsevier Inc. One-photon fluorescent imaging of calcium signals can capture the activity of hundreds of neurons across large fields of view but suffers from crosstalk from neuropil. Shemesh et al. engineer cell-body-targeted variants of fluorescent calcium indicators and show in mice and zebrafish that artifactual spikes and correlations are greatly reduced. | en_US |
dc.language.iso | en | |
dc.publisher | Elsevier BV | en_US |
dc.relation.isversionof | 10.1016/J.NEURON.2020.05.029 | en_US |
dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator | en_US |
dc.type | Article | en_US |
dc.relation.journal | Neuron | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dc.date.updated | 2021-08-13T13:56:09Z | |
dspace.orderedauthors | Shemesh, OA; Linghu, C; Piatkevich, KD; Goodwin, D; Celiker, OT; Gritton, HJ; Romano, MF; Gao, R; Yu, C-CJ; Tseng, H-A; Bensussen, S; Narayan, S; Yang, C-T; Freifeld, L; Siciliano, CA; Gupta, I; Wang, J; Pak, N; Yoon, Y-G; Ullmann, JFP; Guner-Ataman, B; Noamany, H; Sheinkopf, ZR; Park, WM; Asano, S; Keating, AE; Trimmer, JS; Reimer, J; Tolias, AS; Bear, MF; Tye, KM; Han, X; Ahrens, MB; Boyden, ES | en_US |
dspace.date.submission | 2021-08-13T13:56:10Z | |
mit.journal.volume | 107 | en_US |
mit.journal.issue | 3 | en_US |
mit.license | PUBLISHER_CC | |
mit.metadata.status | Authority Work and Publication Information Needed |