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Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers
(National Academy of Sciences (U.S.), 2016-12)
The use of proteasome inhibitors to target cancer’s dependence on altered protein homeostasis has been greatly limited by intrinsic and acquired resistance. Analyzing data from thousands of cancer lines and tumors, we find ...
miRNAs in atherosclerotic plaque initiation, progression, and rupture
(Cell Press/Elsevier, 2015-05)
Atherosclerosis is a chronic immune-inflammatory disorder that integrates multiple cell types and a diverse set of inflammatory mediators. miRNAs are emerging as important post-transcriptional regulators of gene expression ...
An uncertainty approach to assessment of climate change impacts on the Zambezi River Basin
(Springer Netherlands, 2015-04)
Many residents of the Zambezi River Valley are dependent on water-related resources. Greenhouse gas (GHG) emissions may cause a significant change to the climate in the Zambezi Basin in the future, but there is much ...
Search for high-mass resonances decaying into ZZ in pp̅ collisions at √s=1.96 TeV
(American Physical Society, 2012-01)
We search for high-mass resonances decaying into Z boson pairs using data corresponding to 6 fb-1 collected by the CDF experiment in pp̅ collisions at √s=1.96 TeV. The search is performed in three distinct final states: ...
Conceptual short term memory in perception and thought
(Frontiers Research Foundation, 2012-04)
Conceptual short term memory (CSTM) is a theoretical construct that provides one answer to the question of how perceptual and conceptual processes are related. CSTM is a mental buffer and processor in which current perceptual ...
A 0.077 to 0.168 nJ/bit/iteration Scalable 3GPP LTE Turbo Decoder with an Adaptive Sub-Block Parallel Scheme and an Embedded DVFS Engine
(Institute of Electrical and Electronics Engineers (IEEE), 2010-09)
3GPP LTE requires a 100 Mbps of peak bandwidth, and the instantaneous throughput demand changes with different applications. Fixed sub-block parallel turbo decoding scheme introduces bit-error rate (BER) performance drop ...
Measuring active-to-sterile neutrino oscillations with neutral current coherent neutrino-nucleus scattering
(American Physical Society, 2012-07)
Light sterile neutrinos have been introduced as an explanation for a number of oscillation signals at Δm[superscript 2]∼1 eV[superscript 2]. Neutrino oscillations at relatively short baselines provide a probe of these ...
Metagenomic mining of regulatory elements enables programmable species-selective gene expression
(Springer Nature, 2018-03)
Robust and predictably performing synthetic circuits rely on the use of well-characterized regulatory parts across different genetic backgrounds and environmental contexts. Here we report the large-scale metagenomic mining ...
Automatic prediction of consistency among team members' understanding of group decisions in meetings
(Institute of Electrical and Electronics Engineers (IEEE), 2014-12)
Occasionally, participants in a meeting can leave with different understandings of what had been discussed. For meetings that require immediate response (such as disaster response planning), the participants must share a ...
Coded continuous wave meteor radar
(Copernicus GmbH, 2016-03)
The concept of a coded continuous wave specular meteor radar (SMR) is described. The radar uses a continuously transmitted pseudorandom phase-modulated waveform, which has several advantages compared to conventional pulsed ...