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Overview |
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1
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Introduction to Course
Introduction to Functional Magnetic Resonance Imaging
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Safety and Human Subjects Issues, pt. 1 (PDF)
Notes on Human Subjects (PDF)
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Functional Neural Systems |
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2 |
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Overview of Neural Systems (PDF)
Neural Signal Processing (PDF - 1.6 MB)
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3 |
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Visual System
Somatosensory and Motor Systems
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How the Brain Processes Visual Information, Insights & Controversies from Neuroimaging Studies (Kanwisher & Haxby papers) |
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4 |
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Memory Systems
Attention, Motivation, Emotion
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Imaging Physiology |
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5 |
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Overview of Imaging Physiology
Applied Respiratory and Cardiovascular Physiology I |
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Coupling Between Neural Activity and CBF Changes (Iadecola & Mintun papers) |
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6 |
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Applied Respiratory and Cardiovascular Physiology II |
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Impact of Physiological Noise on Analysis and Interpretation of fMRI Data |
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7 |
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Cerebrovascular Anatomy and Neural Regulation of CNS Blood Flow (PDF) |
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8 |
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Neurovascular Coupling
Global vs Regionally Specific Changes in CBF and Metabolism
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Localization in fMRI Data Sets - Comparison with Other Types of Neuroscience Data (Veltman & Disbrow papers) |
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Physics of Image Acquisition |
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9 |
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Overview of Structural and functional MRI Signal Acquisition |
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10 |
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The NMR Signal: Magnetization, Excitation, Detection, NMR Signal, SNR (PDF - 2.2 MB)
Monitoring the NMR Signal: NMR Measurements, T2*, T2, Gradients, Gradient-Echo, Spin-echo
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MR Signal Detection, Phased Array Receiver Coils |
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11 |
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MRI: Spatially Encoding the NMR Signal Frequency, Slice and Phase Encoding, Spin Warp (PDF - 1.7 MB)
Basics of Fast MRI K-space, Fast Imaging, Distortions
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Parallel Image Acquisition Strategies |
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12 |
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Review: Spatial Encoding, k-space
MonRI Contrasts: T1,T2,T2*, Diffusion
Physics of MR Image Acquisition: Review & MRI Contrast (PDF)
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13 |
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BOLD Contrast (part 1) Hemodynamic Response, Temporal, Spatial Resolution (PDF)
Improving fMRI Signal Detection Using Physiological Data
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Temporal and Spatial Resolution (e.g. New Logothetis Articles in Neuron and Nature) |
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14 |
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BOLD Contrast (part 2) Physiological Noise, Field Strength (PDF)
Alternatives to BOLD Review of BOLD, Perfusion vs BOLD, Arterial Spin Labelling, Cerebral Blood Volume
Physics of MR Image Acquisition: Altervatives to BOLD for fMRI (PDF)
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15 |
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Physics of Diffusion Weighted Imaging
Physics and Clinical Applications of Perfusion Weighted Imaging
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ASL (Wong Paper) |
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16 |
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Quantitative fMRI
CBV, CBF & ASL
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17 |
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Mid-term Exam |
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Safety and Human Subjects Issues, pt. 2. Ethics Module |
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Experiment Design |
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18 |
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General Principles of Experimental Design, pt. 1 |
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Paradigm Design (Manoach and Stark) |
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19 |
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General Principles of Experimental Design, pt. 2
Psychological State Variables in Imaging
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Statistical Analysis |
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20 |
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Overview of fMRI Statistical Analysis
Introduction to Univariate Analysis of fMRI Data - part 1
Probability Notes (PDF)
Statistics Notes (PDF)
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Review of Principles of Statistical Inference |
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21 |
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Introduction to Univariate Analysis of fMRI Data - part 2 |
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22 |
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Multivariate Statistical Approaches to fMRI Data Analysis (PDF)
Group Analysis of fMRI Data
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23 |
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Building New Statistical Models for fMRI Data
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24 |
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Statistical Efficiency in fMRI Paradigm Design (PDF) |
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Statistics Q'&'A |
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Structural Analysis |
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25 |
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Surface Based Anatomical Analysis |
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26 |
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Spatial Normalization for Anatomic Analysis
Clinical and Basic Neuroscience Applications of Diffusion Tensor Imaging
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What is Baseline (discussion of Squire paper) |
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27 |
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Final Exam |
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